US 5,891,672 A · Polynucleotides encoding GTP cyclohydrolase II (ribA)

Polynucleotides encoding GTP cyclohydrolase II (ribA)

AssigneeSmithKline Beecham Corporation

InventorsMin Wang, Judith M Ward, Richard Lloyd Warren, Richard Oakley Nicholas, Leslie Marie Palmer, Julie M Pratt, David Justin Charles Knowles, Michael Arthur Lonetto, Jeffrey Mooney, Michael Terence Black, Martin Karl Russell Burnham, Christine Debouck, Jason Craig Fedon, John Edward Hodgson, Deborah Dee Jaworski, Raymond Winfield Reichard, Martin Rosenberg, Christopher Michael Traini, Yi Yi Zhong

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Abstract

The invention provides ribA polypeptides and polynucleotides encoding ribA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribA polypeptides to screen for antibacterial compounds.

Claims9

Dependent claims

An isolated polynucleotide fragment comprising a polynucleotide sequence encoding the amino acid sequence set forth in SEQ ID NO:2.

Dependencies are inferred from the claim text.