Hepatic-directed compounds and reagents for preparation thereof
AssigneeNeoRx Corporation
InventorsLouis J. Theodore, Donald B. Axworthy, John M. Reno
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AssigneeNeoRx Corporation
InventorsLouis J. Theodore, Donald B. Axworthy, John M. Reno
Estimating the term…
Hepatic-directed compounds, reagents useful in making such compounds and associated methods and compositions are discussed. Hepatic-directed compounds are processed by metabolic mechanisms, which generally differ in degree or in kind from the metabolic mechanisms encountered by compounds which are not so directed. Reagents useful in the preparation of hepatic-directed compounds include a hexose cluster characterized by multiple hexose residues connected in an iteratively branched configuration. In one embodiment, the hexose cluster comprises at least four hexose residues with each branch of the configuration having two prongs. In another embodiment, the hexose cluster comprises at least nine hexose residues with each branch of the configuration having three prongs.
A reagent useful in the preparation of hepatic-directed compounds, which reagent includes:
A reagent useful in the preparation of hepatic-directed compounds, which reagent includes:
A reagent useful in the preparation of hepatic-directed compounds, which reagent includes:
Dependencies are inferred from the claim text.