A process for the partial oxidation of hydrocarbons to useful synthesis gas containing hydrogen and carbon monoxide, comprising providing individual streams of a hydrocarbon gas and oxygen or an oxygen-containing gas, each stream being at independent elevated pressure and temperature, injecting said individual streams into admixture with each other through an injector means having a plurality of mixing nozzles to form a gaseous premix, introducing said gaseous premix from the plurality of mixing nozzles, in a time period less than about 5 milliseconds after it is formed, into a partial oxidation reaction zone to form said useful synthesis gas, and recovering said synthesis gas.