Hydrochalcone derivatives, cosmetic compositions containing said derivatives and methods of producing the same
AssigneeMitsui Chemicals, Inc.
InventorsTatsuro Shinomiya, Hiroko Kaminaga, Shohei Nozaki, Masahiro Sakamoto, Shigeharu Morimoto
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Abstract
The present invention can provide cosmetic formulations comprising hydrochalcone compounds of the general formula (I): ##STR1## in which R.sup.1 to R.sup.4 are each independently H or --COR, and R is an alkyl group having 1-20 carbon atoms as effective components, which are highly effective in suppressing pigment deposition and depigmenting the skin and which are very safe to the skin and highly stable during storage.
Claims15
Hydrochalcone compounds of the formula (I):
- ##STR3## in which R.sup.1 to R.sup.4 are each independently H or --COR, and R is an alkyl group having 1-20 carbon atoms.
1,3-bis(2,4-dihydroxyphenyl) propane of the formula (II):
- ##STR4##
A method of producing hydrochalcone compounds of the formula (I):
- ##STR5## in which R.sup.1 to R.sup.4 are each independently H or --COR, and R is an alkyl group having 1-20 carbon atoms,
- which comprises a step of chemically synthesizing said hydrochalcone compounds.
A method of producing a cosmetic composition comprising a hydrochalcone compound of the formula (I):
- ##STR6## in which R.sup.1 to R.sup.4 are each independently H or --COR, and R is an alkyl group having 1-20 carbon atoms, as an effective component, which comprises
- (a) extracting Dioscorea composita plants with suitable solvents to obtain an extract comprising said hydrochalcone compound, and
- (b) mixing said extract with a cosmetic base to obtain the cosmetic composition.
A method of producing a cosmetic composition comprising a hydrochalcone compound of the formula (I):
- ##STR7## in which R.sup.1 to R.sup.4 are each independently H or --COR, and R is an alkyl group having 1-20 carbon atoms, as an effective component, which comprises
- a) a step of extracting Dioscorea composita plants with suitable solvents to obtain an extract containing said hydrochalcone compound,
- b) a step of isolating and purifying said hydrochalcone compound from said extract, and
- c) a step of mixing said purified hydrochalcone compound with a cosmetic base to obtain the cosmetic composition.
Chemically synthesized 1,3-bis(2,4-dihydroxyphenyl)propane of the formula (II):
- ##STR8##
Isolated and purified hydrochalcone compounds of the formula (I):
- ##STR9## in which R.sup.1 to R.sup.4 are each independently H or --COR, and R is an alkyl group having 1-20 carbon atoms.
A method of producing a cosmetic composition comprising a hydrochalcone compound of the formula (I):
- ##STR10## in which R.sup.1 to R.sup.4 are each independently H or --COR, and R is an alkyl group having 1-20 carbon atoms, as an effective component, which method comprises
- (a) chemically synthesizing said hydrochalcone compound, and
- (b) mixing said hydrochalcone compound with a base to obtain a cosmetic composition.
Dependencies are inferred from the claim text.