US 5,880,301 A · Optically active bidentate phosphine ligand palladium complex

Abstract

The present invention provides a novel optically active bidentate phosphine ligand palladium complex of formula (I) or (II) which can be used for the preparation of optically active .beta.-hydroxyketones: ##STR1## wherein Y.sup.- represents an anion pair which may form salt; X represents ##STR2## {wherein R.sup.1 represents hydrogen atom, C.sub.1-6 alkyl group, C.sub.1-6 alkoxyl group, cyano group, nitro group, halogen atom or phenyl group, etc.; m represents 1 or 2; when m is 2, two R.sup.1 s may be same or different}; and A and B each independently represents phenyl group or cyclohexyl group {said phenyl group and cyclohexyl group each is unsubstituted or substituted by R.sup.2 (R.sup.2 has the same meaning as defined in R.sup.1)}).

Claims18

Dependent claims

An optically active bidentate phosphine ligand palladium complex which is prepared from a palladium compound, an optically active bidentate phosphine ligand and silver salt, or from a palladium-optically active bidentate phosphine ligand complex and silver salt.

An optically active bidentate phosphine ligand palladium complex of the formula (I) or (II):

##STR29## wherein Y.sup.- represents an anion pair which may form salt;
X represents ##STR30## {where R.sup.1 represents hydrogen atom, C.sub.1-6 alkyl group, C.sub.2-6 alkenyl group, C.sub.2-6 alkynyl group, C.sub.1-6 alkoxyl group (said alkyl group, alkenyl group, alkynyl group and alkoxyl group each is unsubstituted or substituted by halogen atom, hydroxyl group, tri(C.sub.1-6 alkyl)silyl group, C.sub.1-6 alkyldiphenylsilyl group, di(C.sub.1-6 alkyl)phenylsilyl group, C.sub.1-6 alkoxyl group, C.sub.6-10 aromatic group or heterocyclic group), cyano group, nitro group, halogen atom or phenyl group (said phenyl group is unsubstituted or substituted by C.sub.1-6 alkyl group, C.sub.1-6 alkoxyl group, cyano group, nitro group or halogen atom);
R.sup.3 and R.sup.4 each independently represents C.sub.1-6 alkyl group;
R.sup.5 represents hydrogen atom, COR.sup.6, CO.sub.2 R.sup.6 or CONHR.sup.6 (R.sup.6 represents C.sub.1-6 alkyl group);
R.sup.7 represents hydroxyl group, NR.sup.4.sub.2 or OCOR.sup.4 ;
m represents 1 or 2;
when m is 2, two R.sup.1 s may be same or different};
and
A and B each independently represents phenyl group or cyclohexyl group (said phenyl group and cyclohexyl group are unsubstituted or substituted by R.sup.2 (R.sup.2 has the same meaning as defined in R.sup.1))!.

6 more elements

Dependencies are inferred from the claim text.

Facts

Application

08/894,520Filed 16 Sep 1997

Priority

JP 7-03658024 Feb 1995

Granted

9 Mar 1999

Term ends

Not estimatedThe source records don’t support an estimate.

Classification12 codes

B01J 31/2295
Unsaturated compounds used as ligands: cyclic compounds, e.g. cyclopentadienyls
B01J 31/2409
Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring: with more…
B01J 31/2414
With more than one complexing phosphine-P atom: comprising aliphatic or saturated rings
B01J 31/2452
And phosphine-P atoms as substituents on a ring of the condensed system or on a further attached ring: with more than one complexing phosphine-P atom

Optically active bidentate phosphine ligand palladium complex

Life of this patent

Optically active bidentate phosphine ligand palladium complex

Life of this patent

Abstract

Claims18