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US 5,876,957 AGranted
Methods for applying a reagent to an analytical test device
AssigneeMercury Diagnostics, Inc.
InventorsJoel S. Douglas, John M. Gleisner
Life of this patent
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Abstract
This invention provides methods and apparatus for applying a reagent to an analytical test device. The methods and apparatus employ a nozzle and a flexible restrictor to accurate control the amount of reagent applied to the test device. The analytical test devices prepared by the methods of this invention are used to determine the presence or the quantity of an analyte in a liquid sample, such as whole blood.
Claims20
A method for applying a reagent to a test device comprising:
- (a) providing a test device comprising a substrate and a test pad attached to the substrate;
- (b) providing a fluid delivery system comprising a nozzle and a flexible restrictor attached to the nozzle for delivery of a reagent from the nozzle to the test pad;
- (c) applying a reagent comprising an indicator system and an oxidase enzyme or a peroxidase enzyme in a predetermined amount and at a predetermined pressure through the nozzle and the flexible restrictor to the test pad.
An apparatus for applying a reagent to a test device comprising a substrate and a test pad, said apparatus comprising:
- (a) a fluid delivery system comprising a nozzle and a flexible restrictor for delivery of the reagent to the test pad;
- (b) a support positioned under the fluid delivery system for supporting the test device;
- and
- (c) means for moving the test device under the fluid delivery system.
1 more element
Dependencies are inferred from the claim text.