Bioactive-gel compositions and methods
AssigneeUSBiomaterials Corporation
InventorsJipin Zhong, David C. Greenspan
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Abstract
A process for making bioactive glasses is described including preparing a reaction mixture of reactants capable of forming a sol-gel, aging the reaction mixture, near equilibrium drying a gel resulting from the reaction mixture, and heating the -near equilibrium-dried gel described. Also described are near equilibrium-dried bioactive glass compositions.
Claims27
A process for making bioactive glasses comprising:
- preparing a reaction sol capable of forming a sol-gel;
- aging said reaction mixture;
- near equilibrium drying a gel resulting from the reaction mixture, and;
- heating the near equilibrium dried gel at a temperature above ambient.
A process for making bioactive glasses by a sol-gel process, the improvement comprising near equilibrium drying a sol-gel.
A sol-gel process for making a bioactive glass monolith comprising:
- preparing a reaction mixture capable of forming a bioactive sol-gel monolith;
- casting the reaction mixture into a mold of desired shape;
- aging said reaction mixture cast in said mold at a temperature elevated above ambient;
- near equilibrium drying the reaction mixture, and;
- heating the reaction mixture.
A composition for the treatment of orthopedic conditions comprising a bioactive sol gel glass capable of forming an HCA layer within 12 hours of exposure to simulated body fluids.
Dependencies are inferred from the claim text.