Compositions useful as a cannabinoid receptor probe
AssigneeUniversity of Connecticut
InventorsAlexandros Makriyannis, Yan Guo, Vasiliki Abadji
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Abstract
A composition of matter, comprising a cannabinol compound having the structure ##STR1## wherein, Q is --C(R.sup.1)(Y.sup.1)--(CH.sub.2).sub.n --Z.sup.1 ; R.sup.1 is --H or --CH.sub.3 ; Y.sup.1 is --CH.sub.3 or Y.sup.2 ; Y.sup.2 is --N.sub.3 or --NCS; n is 4 or 6; Z.sup.1 is --H, when Y.sup.1 is Y.sup.2, or is Z.sup.2, when Y.sup.1 is --CH.sub.3 ; and Z.sup.2 is --N.sub.3 or --NCS. This composition has good binding affinity to the cannabinoid receptor and therefore, is useful as a receptor probe.
Claims4
A compound represented by the following structural formula:
- ##STR6## wherein:
- n is an integer from three through seven;
- and
- Z.sup.1 is --N.sub.3 or --NCS.
A compound represented by the following structural formula:
- ##STR7## wherein:
- R.sup.1 is --H or --CH.sub.3 ;
- n is an integer from three through seven;
- and
- Z.sup.1 is --N.sub.3 or --NCS.
Dependencies are inferred from the claim text.