Method of therapy comprising an osmotic caplet
AssigneeAlza Corporation
InventorsPatrick S.-L. Wong, Felix Theeuwes, George V. Guittard, Atul D. Ayer
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Abstract
An osmotic caplet is disclosed comprising an osmotic caplet exit for delivering a preselected dose of drug to a patient in need of therapy.
Claims8
A method for administering 300 ng to 1200 mg of an antiviral drug to a patient, which method comprises orally administering 300 ng to 1200 mg of the drug to the patient from an osmotic caplet comprising:
- (1) an oblong body;
- (2) a semipermeable wall that forms the osmotic oblong body;
- (3) a dose of 300 ng to 1200 mg of the drug in the osmotic caplet;
- (4) a passageway for maximizing the delivery of the drug from the osmotic caplet, said passageway comprising a convex surface having a radius of curvature at least equal to the radius of the osmotic oblong caplet, the osmotic caplet administering the drug by:
- (5) imbibing fluid into the osmotic caplet for hydroactivating the osmotic caplet;
- thereby,
- (6) administering the drug to the patient from the osmotic caplet over time.
A method for administering 300 ng to 1200 mg of a drug to a patient, which method comprises orally administering 300 ng to 1200 mg of the drug to the patient from an osmotic caplet comprising:
- (1) a wall comprising a semipermeable composition that surrounds;
- (2) an oblong body;
- (3) 300 ng to 1200 ng of drug in the osmotic caplet;
- and,
- (4) a passageway comprising means for maximizing the delivery of drug from the osmotic caplet, said passageway comprising a convex surface with a radius of curvature at least equal to the radius of the osmotic oblong caplet.
A method for administering 300 ng to 1200 mg of a drug to a patient, which method comprises orally administering 300 ng to 1200 mg of the drug to the patient from an osmotic caplet comprising:
- (1) a wall comprising a semipermeable composition that surrounds;
- (2) an oblong body;
- (3) 300 ng to 1200 mg of drug in the osmotic caplet;
- and,
- (4) a passageway comprising means for maximizing the delivery of drug from the osmotic caplet, which passageway is characterized by an area equal to 0.1 to 0.9 of the cross-section area of the oblong body of the osmotic caplet.
Dependencies are inferred from the claim text.