Specific eatable taste modifiers
AssigneeBioResearch Inc.
InventorsRobert J. Kurtz, William D. Fuller
Life of this patent
Estimating the term…
Abstract
Ingestible compounds which are substantially tasteless and which have been found to be effective reducers or eliminators of undesirable tastes for eatables.
Claims87
A composition comprising an eatable having a burning taste and at least one tastand in an amount of about 0.0000001 to about 300% by weight, based on the weight of the eatable, in an amount sufficient to reduce said burning taste, said tastand being selected from the group of compounds having the structure:
- ##STR94## wherein at least one of the substituents R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is selected from the group consisting of substituents capable of participating in a hydrogen bond and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are independently selected from the group consisting of:
- H, alkyl, substituted alkyl, alkoxy, substituted alkoxy, aryl, substituted aryl, alkylene, substituted alkylene, aminoacyl, substituted aminoacyl, aryloxy, substituted aryloxy, hydroxy, nitro, amino, substituted amino, cyano, halogen, aralkoxy, substituted aralkoxy, acyl, substituted acyl, arylacyl, substituted arylacyl, trifluoroacetyl, benzoyl, substituted benzoyl, alkylamino, substituted alkylamino, dialkylamino, substituted dialkylamino, trialkylamino, substituted trialkylamino, carbonates, substituted carbonates, alkylcarbonates, substituted alkylcarbonates, arylcarbonates, substituted arylcarbonates, acylamino, substituted acylamino, guanidino, substituted guanidino, alkylguanidino, substituted alkylguanidino, acylguanidino, substituted acylguanidino, arylguanidino, substituted arylguanidino, alkyurethanes, substituted alkyurethanes, arylurethanes, substituted arylurethanes, ureas, substituted ureas, mono- or di- or tri- substituted ureas, alkylureas, substituted alkylureas, an O, S or N glycoside, or a phosphorylated glycoside where the glycoside is a monosaccharide, a disaccharide, a trisaccharide, an oligosaccharide, a substituted mono-, di-, tri-, or oligosaccharide, CHO, substituted CHO, COCH.sub.3, substituted COCH.sub.3, CH.sub.2 CHO, substituted CH.sub.2 CHO, COOH, CH.sub.2 COOH, substituted CH.sub.2 COOH, COOCH.sub.3, substituted COOCH.sub.3, OCOCH.sub.3, substituted OCOCH.sub.3, CONH.sub.2, substituted CONH.sub.2, NHCHO, substituted NHCHO, SCH.sub.3, substituted SCH.sub.3, SCH.sub.2 CH.sub.3, substituted SCH.sub.2 CH.sub.3, CH.sub.2 SCH.sub.3, substituted CH.sub.2 SCH.sub.3, SO.sub.3 H, SO.sub.2 NH.sub.2, substituted SO.sub.2 NH.sub.2, SO.sub.2 CH.sub.3, substituted SO.sub.2 CH.sub.3, CH.sub.2 SO.sub.3 H, substituted CH.sub.2 SO.sub.3 H, cycloalkyl, substituted cycloalkyl, heterocyclic, substituted heterocyclic, polycyclic, substituted polycyclic, and CH.sub.2 SO.sub.2 NH.sub.2, arylureas, substituted arylureas, multiple substituted arylureas, an acid group of the structure ZO.sub.q H.sub.r wherein Z is an element selected from the group consisting of carbon, sulfur, boron or phosphorus, q is an integer from 2 to 3 and r is an integer from 1 to 3;
- carboxylic acid ester, substituted carboxylic acid ester, carboxamide, substituted carboxamide, N-alkyl carboxamide, substituted N-alkyl carboxamide, di-alkyl carboxamides, substituted di-alkyl carboxamides, and/or two substituents together represent an aliphatic chain linked to a phenyl ring at two positions, either directly or via a an oxygen, nitrogen or sulfur group, any H on N, S, or O, may be substituted with one of the following substituents:
- alkyl, substituted alkyl, dialkyl, substituted dialkyl, aralkyl, substituted aralkyl, aryl, substituted aryl, diaryl, substituted diaryl, acyl, substituted acyl, cycloalkyl, substituted cycloalkyl, benzoyl, substituted benzoyl, trifluoroacetyl, alkyloxycarbonyl, substituted alkyloxycarbonyl, aryloxycarbonyl, substituted aryloxycarbonyl, alkylaminocarbonyl, substituted alkylaminocarbonyl, arylaminocarbonyl, substituted arylaminocarbonyl, amidines, substituted amidines, alkylamidines, substituted alkylamidines, arylamidines, substituted arylamidines, a monosaccharide, substituted a monosaccharide, a disaccharide, substituted disaccharide, a trisaccharide, substituted trisaccharide, an oligosaccharide, substituted oligosaccharide, phosphorylated saccharides, substituted phosphorylated saccharides, arylacyl, substituted arylacyl, alkylene, substituted alkylene, heterocyclic, substituted heterocyclic, polycyclic, substituted polycyclic, cyano, nitro, any H on N, S, or O, may be substituted with one of the above substituents, in any combination,
- and physiologically accepted salts of any and/or all of the foregoing.
A composition comprising ibuprofen, having a burning taste, and 2,4-dihydroxybenzoic acid in an amount sufficient to reduce said burning taste.
A composition comprising ethanol, having a burning taste, and 2,4-dihydroxybenzoic acid in an amount sufficient to reduce said burning taste.
A composition comprising peppers or pepper extract, having a burning taste, and 2,4-dihydroxybenzoic acid in an amount sufficient to reduce said burning taste.
A composition comprising capsaicin or capsaicin analogues, having a burning taste, and 2,4-dihydroxybenzoic acid in an amount sufficient to reduce said burning taste.
Dependencies are inferred from the claim text.