gidB
AssigneeSmithKline Beecham Corporation
InventorHoward Kallender
Life of this patent
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Abstract
The invention provides gidB polypeptides and DNA (RNA) encoding gidB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gidB polypeptides to screen for antibacterial compounds.
Claims22
An isolated recombinant polynucleotide segment encoding SEQ ID NO:2.
An isolated recombinant polynucleotide segment encoding a mature polypeptide expressed by the gidB gene contained in Streptococcus pnuemoniae 0100993 in NCIMB Deposit Number 40800.
An isolated recombinant polynucleotide segment comprising a nucleotide sequence which is identical to a reference sequence having nucleotide position 201 to 911 as shown in SEQ ID NO:1, except that the nucleotide sequence includes up to five substitutions, insertions or deletions for every 100 nucleotides of the reference sequence from nucleotide position 201 to 911 as shown in of SEQ ID NO:1.
An isolated recombinant polynucleotide segment comprising a nucleotide sequence from position 201 to 911 inclusive of the polynucleotide sequence set forth in SEQ ID NO:1.
Dependencies are inferred from the claim text.