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US 5,866,347 AGranted
Method of identifying persons susceptible to autoimmune neuropsychiatric disorders
AssigneeThe United States of America as represented by the Department of Health and Human Services
InventorsSusan E. Swedo, Henrietta L. Leonard, John B. Zabriskie
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Abstract
A method of identifying individuals who have, or who are at risk of developing, autoimmune neuropsychiatric disorders is disclosed. The invented method relies on detection of the B lymphocyte antigen, D8/17. The invented method can conveniently be carried out as a simple blood test.
Claims16
A method of determining whether a human subject has susceptibility to an autoimmune neuropsychiatric disorder other than Sydenham's chorea, comprising the steps of:
- (a) obtaining a sample containing B lymphocytes from the subject;
- and
- (b) testing the B lymphocytes for the presence of the antigen recognized by the monoclonal antibody produced by the ATCC HB8783 cell line, wherein the presence of said antigen indicates that the subject has a susceptibility to said autoimmune neuropsychiatric disorder.
Dependencies are inferred from the claim text.