Arylglycinamide derivatives and pharmaceutical compositions containing these compounds

An arylglycinamide derivative of the formula I ##STR74## or the pharmaceutically acceptable salts thereof, wherein

• Ar denotes unsubstituted or mono- to penta-substituted phenyl, or unsubstituted or mono- or di-substituted naphthyl, in which the substituents of the phenyl and naphthyl independently of each other denote halogen (F, Cl, Br, I), (C.sub.1-4)alkyl, O--( C.sub.1-4)alkyl, CF.sub.3, OCF.sub.3 or NR.sup.9 R.sup.10 (wherein R.sup.9 and R.sup.10 independently of each other denote H, methyl or acetyl);
• R.sup.1 and R.sup.2 together with the N to which they are bound form a 6-membered ring of the formula ##STR75## wherein X denotes CR.sup.7 R.sup.8, wherein
• R.sup.7 and R.sup.8 have the following meanings:
• a) R.sup.7 is ##STR76## R.sup.8 is H, --CONH.sub.2, --NHC(O)CH.sub.3 or --N(CH.sub.3)C(O)CH.sub.3, R.sup.3 denotes H, (C.sub.1-4)alkyl, unsubstituted or mono- to tri-substituted phenyl, wherein the substituents independently of one another represent halogen (F, Cl, Br, I), (C.sub.1-4)alkyl, O--(C.sub.1-4)alkyl, CF.sub.3, OCF.sub.3 or NR.sup.9 R.sup.10 (wherein R.sup.9 and R.sup.10 independently of one another denote H, methyl or acetyl);
• R.sup.4 denotes (CH.sub.2).sub.m phenyl or (CH.sub.2).sub.m naphthyl, wherein m is 1, 2 or 3 and phenyl may be substituted by 1 to 3 substituents, wherein the substituents independently of one another are halogen (F, Cl, Br, I),
• (C.sub.1-4)alkyl, O--(C.sub.1-4)alkyl, CF.sub.3, OCF.sub.3 or NR.sup.9 R.sup.10 (wherein R.sup.9 and R.sup.10 independently or one another denote H, methyl or acetyl);
• and
• R.sup.5 denotes H, (C.sub.1-4)alkyl, (C.sub.3-6)cycloalkyl or CH.sub.2 COOH.