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US 5,861,495 AGranted
Human zinc binding proteins
AssigneeIncyte Pharmaceuticals, Inc.
InventorsJennifer L. Hillman, Janice Au-Young, Roger Coleman, Surya K. Goli
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AssigneeIncyte Pharmaceuticals, Inc.
InventorsJennifer L. Hillman, Janice Au-Young, Roger Coleman, Surya K. Goli
Estimating the term…
The present invention provides three zinc binding proteins (designated individually as ZB-1, ZB-2, and ZB-3, and collectively as ZB) and polynucleotides which identify and encode ZB. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding ZB and a method for producing ZB. The invention also provides for use of ZB and agonists, antibodies, or antagonists specifically binding ZB, in the prevention and treatment of diseases associated with expression of ZB. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding ZB for the treatment of diseases associated with the expression of ZB. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding ZB.
An isolated and purified polynucleotide sequence encoding a polypeptide comprising the amino acid sequence of SEQ ID NO:1.
An isolated and purified polynucleotide sequence consisting of SEQ ID NO:2.
Dependencies are inferred from the claim text.