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US 5,859,252 AGranted
Processes for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof
AssigneeHoechst Marion Roussel, Inc.
InventorsGary A. Flynn, Thomas D. Bannister, Michael J. Genin, Douglas W. Beight
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Abstract
The present invention relates to novel processes for preparing intermediates of the formula I ##STR1## and to novel intermediates thereof which are useful in the preparation of inhibitors of enkephalinase and angiotensin converting enzyme.
Claims3
A compound of the formula ##STR49## wherein Ar is a radical selected from the group consisting of ##STR50## wherein X.sub.1 is selected from the group consisting of S and NH;
- X.sub.2 is selected from the group consisting of S, O, and NH;
- and
- R is selected from the group consisting of hydrogen, hydroxy, phenyl, and C.sub.1 -C.sub.4 alkoxy.
Dependencies are inferred from the claim text.