Silicone derivatives, their production and use

A compound represented by general formula (3):

• ##STR30## wherein each R, which may be the same or different, represents hydrogen or a linear, branched-chain or cyclic hydrocarbon group of 1 to 8 carbon atoms;
• m, n and h each represent integers from 1 to 6;
• "a" represents an integer from 1 to 400;
• two of the Ys are a nitrogen atom and the remaining Y is a carbon atom;
• q represents an integer from 0 to 10;
• p represents an integer from 1 to 3;
• and, when p is 1 or 2, a hydroxyl group, an amino group which may be substituted by a linear or branched alkyl group of 1 to 6 carbon atoms, a halogen atom, a carboxyl group, a linear or branched alkyl group of 1 to 6 carbon atoms, or a linear or branched alkoxyl group of 1 to 6 carbon atoms, or as well a hydrogen atom, is bound to a residual carbon atom of the ring;
• and
• (i) when q is from 1 to 10, A1 and A2 are each represented by general formula (4):
• ##STR31## wherein R, m, n, h, "a" and Y have the same meanings as given above, and A1' and A2' each represents hydrogen atoms, hydroxyl groups, amino groups which may be substituted by linear or branched alkyl groups each having 1 to 6 carbon atoms, halogen atoms, carboxyl groups, linear or branched alkyl groups each having 1 to 6 carbon atoms, or linear or branched alkoxyl groups each having 1 to 6 carbon atoms;
• or A1 and A2 are each represented by general formula (5):
• ##STR32## wherein R, m, n, h and "a" have the same meanings as given above;
• or A1 and A2 each represent hydrogen atoms, hydroxyl groups, amino groups which may be substituted by linear or branched alkyl groups each having 1 to 6 carbon atoms, halogen atoms, carboxyl groups, linear or branched alkyl groups each having 1 to 6 carbon atoms, or linear or branched alkoxyl groups each having 1 to 6 carbon atoms;
• and
• (ii) when q is 0, general formula (3) is represented by general formula (6):
• ##STR33##

A compound represented by the following general formula which is obtained by allowing a side-chain amino silicone to react with a reactive group-containing pyrimidinyl compound:

• ##STR34## wherein each R, which may be the same or different, represents hydrogen or a linear, branched-chain or cyclic hydrocarbon group of 1 to 8 carbon atoms;
• m, n and h each represent integers from 1 to 6;
• "a" and "b" each represent integers of 1 or more, "d" represents an integer of 0 or more, and "a+b+d" represents an integer of 400 or less;
• and "a", "b" and "d" each show the relative number but do not specify the order of arrangement;
• two of the Ys are a nitrogen atom and the remaining Y is a carbon atom;
• and wherein each X is independently selected from the group consisting of hydrogen, halogen, hydroxyl, amino which may be substituted by a linear or branched alkyl group of 1 to 6 carbon atoms, carboxyl, alkyl having 1 to 6 carbon atoms, alkoxy having 1 to 6 carbon atoms, and ##STR35## wherein B is R or ##STR36## wherein two of the Ys are a nitrogen atom and the remaining Y is a carbon atom.

A composition comprising an admixture of (i) a compound and (ii) a liquid oil or silicone oil, said compound represented by the formula:

• ##STR40## wherein at least one X is ##STR41## and each remaining X is independently selected from the group consisting of hydrogen, halogen, hydroxyl, amino which may be substituted by linear or branched alkyl groups each having 1 to 6 carbon atoms, carboxyl, alkyl having 1 to 6 carbon atoms, and alkoxy having 1 to 6 carbon atoms;
• each R, which may be the same or different, represents hydrogen or a linear, branched-chain or cyclic hydrocarbon group of 1 to 8 carbon atoms;
• m and n each represents integers from 1 to 6;
• h represents integers from 0 to 6;
• "a" represents an integer from 1 to 400;
• and
• wherein B is R or ##STR42## wherein two of the Ys are a nitrogen atom and the remaining Y is a carbon atom.

A gel comprising an admixture of (i) a compound and (ii) a liquid oil or silicone oil, said compound represented by the formula:

• ##STR51## wherein at least one X is ##STR52## and each remaining X is independently selected from the group consisting of hydrogen, halogen, hydroxyl, amino which may be substituted by a linear or branched alkyl group of 1 to 6 carbon atoms, carboxyl, alkyl having 1 to 6 carbon atoms, and alkoxy having 1 to 6 carbon atoms;
• each R, which may be the same or different, represents hydrogen or a linear, branched-chain or cyclic hydrocarbon group of 1 to 8 carbon atoms;
• m and n each represents integers from 1 to 6;
• h represents integers from 0 to 6;
• "a" represents an integer from 1 to 400;
• and
• wherein B is hydrogen, R or ##STR53## wherein two of the Ys are a nitrogen atom and the remaining Y is a carbon atom.

A base for a cosmetic or a pharmaceutical preparation, the base comprising an admixture of (i) a compound and (ii) a liquid oil or silicone oil, said compound represented by the formula:

• ##STR62## wherein at least one X is ##STR63## and each remaining X is independently selected from the group consisting of hydrogen, halogen, hydroxyl, amino which may be substituted by a linear or branched alkyl group of 1 to 6 carbon atoms, carboxyl, alkyl having 1 to 6 carbon atoms, and alkoxy having 1 to 6 carbon atoms;
• each R, which may be the same or different, represents hydrogen or a linear, branched-chain or cyclic hydrocarbon group of 1 to 8 carbon atoms;
• m and n each represents integers from 1 to 6;
• h represents integers from 0 to 6;
• "a" represents an integer from 1 to 400;
• and
• wherein B is R or ##STR64## wherein two of the Ys are a nitrogen atom and the remaining Y is a carbon atom.