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US 5,859,188 AGranted
Method for discovering novel anthelmintic compounds
AssigneePharmacia & Upjohn Company
InventorsTimothy G. Geary, Jerry W. Bowman, Alan R. Friedman
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Abstract
The present invention provides a novel radioactive neuropeptide represented by the formula Lys-His-Glu-Tyr.sup.--I -Leu-Arg-Phe-amide. The invention also provides a method for detecting anthelmintic activity of a compound using the novel neuropeptide of the present invention in a receptor binding assay. The novel radioactive neuropeptide has potent bioactivity in Ascaris suum neuromuscular strips, and therefore is particularly useful for high volume screening for potential anthelmintic compounds.
Claims8
A peptide of the formula Lys-His-Glu-Tyr.sup.--I -Leu-Arg-Phe-amide.
Dependencies are inferred from the claim text.