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US 5,859,185 AGranted
HCMV-specific peptides, agents therefor and the use thereof
AssigneeBehringwerke Aktiengesellschaft
InventorsWerner Stuber, Leszek Wieczorek, Robert Ziegelmaier
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Abstract
The invention relates to peptides for the immunochemical determination of human cytomegalovirus (HCMV)-specific antibodies and HCMV antigens, and to agents suitable for this method and to the use thereof.
Claims62
A peptide which reacts specifically with antibodies against HCMV,
- wherein said peptide consists of at least one amino-acid sequence selected from the group consisting of
- AS.sub.e -gly ala gly ala ala ile leu-BS.sub.m (peptide 1) (SEQ ID NO.:
- 1),
- CS.sub.n -arg ala trp ala leu-Ds.sub.o (peptide 2) (SEQ ID NO.:2), and
- ES.sub.p -ala ser arg asp ala ala-Fs.sub.q (peptide 3) (SEQ ID NO.:3)
- where AS, BS, CS, DS, ES and FS are, independently of one another, any appropriate amino acid and
- e is an integer from 0 to 14, and m is an integer from 0 to 7, or e is an integer from 0 to 2 and m is an integer from 0 to 19,
- n and o are, independently of one another, integers from 0 to 18, and
- p and q are, independently of one another, integers from 0 to 11,
- wherein said peptide reacts specifically with antibodies against HCMV.
7 more elements
Dependencies are inferred from the claim text.