SF caspase-1 and compositions for making and methods of using the same

Abstract

A substantially pure protein, Caspase-1, is disclosed. An isolated nucleic acid molecule that comprises a nucleic acid sequence that encodes Caspase-1, is disclosed. An isolated nucleic acid molecule consisting of a nucleic acid sequence that encodes Caspase-1, or a fragment thereof having at least 10 nucleotides is disclosed. Recombinant expression vector comprising a nucleic acid sequence that encodes Caspase-1 and host cells comprising the recombinant expression vector are disclosed. Oligonucleotide molecule comprising a nucleotide sequence complimentary to a nucleic acid sequence that encodes Caspase-1 of at least 5 nucleotides are disclosed. Antibodies that binds to an epitope on Caspase-1 are disclosed. Methods of identifying modulators and substrates of Caspase-1 are disclosed.

Dependencies are inferred from the claim text.