Constitutive pseudohyphal growth yeast mutants
AssigneesIowa State University Research Foundation, Inc., Institut Pasteur, Institut National de la Sante et de la Recherche Medicale
InventorsAlan M. Myers, Pascal Madaule
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Abstract
An isolated gene and mutations thereof capable of imparting constitutive pseudohyphal growth to S. cerevisiae is provided. The isolated wild type gene referred to as ELM1 is also capable of coding for a novel protein kinase that determines the yeast morphology and specific physiological properties.
Claims13
A genetically modified S. cerevisiae yeast strain containing a ELM1 mutant gene in a genetic background selected from the group consisting of W303, NY13, .SIGMA.1278b, and combinations thereof.
A genetically modified S. cerevisiae yeast strain selected from the group consisting of NW.DELTA.elm1, .SIGMA.W.DELTA.elm1, and N.SIGMA..DELTA.elm1, WW.DELTA.elm1, .SIGMA..SIGMA..DELTA.elm1, NN.DELTA.elm1, a/.alpha.Elm2, and a/.alpha.Elm3.
Dependencies are inferred from the claim text.