Hiss
AssigneeSmithKline Beecham Corporation
InventorsJames R. Brown, Elizabeth J Lawlor, Raymond W Reichard
Life of this patent
Estimating the term…
Abstract
The invention provides hisS polypeptides and DNA (RNA) encoding hisS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing hisS polypeptides to screen for antibacterial compounds.
Claims19
An isolated polynucleotide segment encoding SEQ ID NO:2.
An isolated polynucleotide segment comprising a nucleotide sequence which is identical to the reference sequence of SEQ ID NO:1, except that the nucleotide sequence includes up to five substitutions, insertions or deletions for every 100 nucleotides of the reference sequence of SEQ ID NO:1.
An isolated polynucleotide segment comprising a nucleotide sequence which is identical to the reference sequence of SEQ ID NO:1, except that the nucleotide sequence includes up to ten substitutions, insertions or deletions for every 100 nucleotides of the reference sequence of SEQ ID NO:1.
An isolated polynucleotide segment comprising a nucleotide sequence which is identical to the reference sequence of SEQ ID NO:1, except that the nucleotide sequence includes up to twenty substitutions, insertions or deletions for every 100 nucleotides of the reference sequence of SEQ ID NO:1.
An isolated polynucleotide segment comprising a nucleotide sequence which is identical to the reference sequence of SEQ ID NO:1, except that the nucleotide sequence includes up to thirty substitutions, insertions or deletions for every 100 nucleotides of the reference sequence of SEQ ID NO:1.
An isolated polynucleotide segment comprising SEQ ID NO:1.
An isolated polynucleotide segment comprising a nucleotide sequence from position 1 to 1308 inclusive of the polynucleotide sequence set forth in SEQ ID NO:1.
Dependencies are inferred from the claim text.