CDNA encoding a LEA-motif developmental protein homologous to avian px19
AssigneeIncyte Pharmaceuticals, Inc.
InventorsJennifer L. Hillman, Surya K. Goli
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Abstract
px19 is an avian gene recently identified as a bromodexoyuridine (BrdU)-sensitive transcript associated with hematopoiesis in early chick development. Its translation product contains an "LEA" (late embryogenesis abundant) motif which had previously been observed only in plant seed proteins. The present invention provides nucleic acids encoding a human LEA motif protein (HuLEAP) homologous to the avian px19 gene product. Also provided are expression vectors, transformed host cells, and methods of using them to produce recombinant HuLEAP polypeptides.
Claims8
An isolated and purified polynucleotide comprising SEQ ID NO:2.
An isolated and purified polynucleotide encoding a polypeptide comprising the amino acid sequence of SEQ ID NO:1.
A hybridization probe comprising the isolated and purified polynucleotide of claim 5 and a detectable label.
Dependencies are inferred from the claim text.