Picosulfate-containing preparation for colonic evacuation
OwnerThomas Julius Borody, Walter George Shortis +1inventors
InventorsThomas Julius Borody, Walter George Shortis, Nicolas Peter Shortis
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Abstract
An osmotic colonic evacuant in solid dosage form, which comprises a phosphate based laxative or a sulfate based laxative and preferably comprises sodium picosulfate and an antacid, is used preferably in conjunction with 250 ml to 1,500 ml diluent, alone or as part of a sequential pack, to evacuate the colon, to treat small bowel bacterial overgrowth, irritable bowel syndrome, and acute or chronic bacterial bowel infections.
Claims48
The method of evacuating a patient's colon, comprising orally administering to said patient a treatment regimen of an osmotic colonic evacuant in solid form together with a diluent of volume of from 1,000 ml to 1,500 ml, wherein said colonic evacuant comprises a sulfate based laxative comprising a picosulfate, without administration of a polyethylene glycol electrolyte lavage solution.
A method of treating small bowel bacterial overgrowth or irritable bowel syndrome in a patient in need of such treatment, comprising administering to said patient a treatment regimen of an osmotic colonic evacuant in solid form together with a diluent of volume of from 1,000 ml to 1,500 ml, wherein said colonic evacuant comprises a sulfate based laxative comprising a picosulfate.
A method of treating acute or chronic bacterial bowel infection in a patient in need of such treatment, comprising administering to said patient a treatment regimen of an osmotic colonic evacuant in solid form together with a diluent of volume of from 1,000 to 1,500 ml, wherein said colonic evacuant comprises a sulfate based laxative comprising a picosulfate.
A sequential pack for oral administration of at least two treatment regimens comprising a first treatment regimen comprising an osmotic colonic evacuant in solid oral dosage form, in unit dosage form adapted and presented for a first administration period, together with a second treatment regimen comprising an osmotic evacuant in solid oral dosage form, in unit dosage form adapted and presented for a second administration period, wherein said osmotic colonic evacuant comprises a sulfate based laxative comprising a picosulfate.
Dependencies are inferred from the claim text.