Lactobacillus acidophilus to inhibit cryptosporidiosis in mammals
AssigneeAbbott Laboratories
InventorsBryan Warren Wolf, Keith Allen Garleb
Life of this patent
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Abstract
Cryptosporidium parvum (the cause of cryptosporidiosis) has become one of the most common enteropathogens causing diarrhea worldwide. Symptoms associated with cryptosporidiosis are very debilitating especially in the immunocompromised subject (e.g., AIDS patient). Clinical features include severe, chronic diarrhea, abdominal cramps, fatigue, weight loss, etc. which lead to increased health care costs and increased mortality. There is described herein a method of inhibiting the severity of Cryptosporidium parvum infection by enterally administering a therapeutically effective amount of Lactobacillus acidophilus.
Claims15
A method for treating a mammal to inhibit infection by Cryptosporidium parvum or to increase the resistance to Cryptosporidium parvum infection, said method comprising enterally administering to said mammal a composition comprising an anti-infective probiotic component consisting essentially of an amount of Lactobacillus acidophilus effective to inhibit or increase the resistance to infection by Cryptosporidium parvum.
Dependencies are inferred from the claim text.