Compositions and methods for enhancing contact lens wearability
AssigneeAllergan, Inc.
InventorsJoseph G. Vehige, James P. Currie
Life of this patent
Estimating the term…
Abstract
Compositions and methods for treating a contact lens very effectively and conveniently provide enhanced contact lens wearability by reducing the actual or perceived ocular sensitivity which results from exposing a contact lens to non-oxidative antimicrobial components. The present system takes advantage of inactivating or deactivating a non-oxidative antimicrobial component located on or in a contact lens to reduce the ocular sensitivity caused by placing the lens in the eye.
Claims12
A method for enhancing the wearability of a contact lens which comprises:
- contacting a contact lens on or in which is located a non-oxidative antimicrobial component selected from the group consisting of polycationic antimicrobial component and mixtures thereof with a liquid medium containing an amount in the range of about 5% (w/v) or less effective to inactivate substantially all the non-oxidative antimicrobial component located on or in said contact lens of an inactivating component selected from the group consisting of anionic cellulose derivatives, anionic acrylic acid-containing polymers, anionic methacrylic acid-containing polymers, anionic amino acid-containing polymers and mixtures thereof at conditions effective to inactivate said non-oxidative antimicrobial component located on or in said contact lens.
A composition for enhancing the wearability of a contact lens which comprises:
- an aqueous liquid medium;
- an inactivating component soluble in said aqueous liquid medium, selected from the group consisting of anionic cellulose derivatives, anionic acrylic acid-containing polymers, anionic methacrylic acid-containing polymers, anionic amino acid-containing polymers and mixtures thereof and present in an amount in the range of about 5% (w/v) or less effective to inactivate substantially all of a non-oxidative, polycationic antimicrobial component located on or in a contact lens contacted with said composition;
- and
- a preservative component selected from the group consisting of per-salts, peroxides, alcohols, sorbic acid, chlorine dioxide precursors and mixtures thereof in an amount in a range of about 0.000001% to about 0.05% (w/v) effective to preserve said composition, the preserving activity of said preservative component being effective in the presence of said inactivating component, wherein said preservative component has a reduced propensity to cause discomfort in a human eye relative to the non-oxidative, polycationic antimicrobial component located on or in a contact lens contacted with said composition.
Dependencies are inferred from the claim text.