Column for capillary chromatographic separations and method of manufacturing same
AssigneeHewlett-Packard Company
InventorsMonika Dittmann, Gerard Rozing, Klaus K. Unger, Thomas Adam
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Abstract
A column for capillary chromatographic separations, for example high performance liquid chromatography, capillary electrochromatography, or supercritical chromatography, comprises a column bed of packing material arranged in the inner bore of a capillary, wherein said bed of packing material is completely immobilized by a thermal treatment. The thermal treatment preferably comprises moving a heating wire along the column while applying pressure to the column using a high pressure pump.
Claims3
A method of manufacturing a column for capillary chromatographic separations, comprising the steps of:
- filling stationary phase packing material into and along a determined length of a capillary;
- immobilizing all of the stationary phase packing material inside the capillary by application thereto of a thermal treatment along an entirety of said determined length;
- and
- applying pressure to an inlet side of the capillary during the thermal treatment to enable a flow of a portion of said stationary phase packing material to a colder region of said capillary where said portion solidifies and acts to bind said stationary phase packing material.
Dependencies are inferred from the claim text.