Process for the preparation of fluoroanilines from fluorinated nitrated benzene compounds
AssigneeRhone-Poulenc Chimie
InventorsGeorges Cordier, Gilbert Guidot, Philippe Marion, Claude Mercier
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Abstract
The instant invention relates to a process for the preparation of fluoroanilines of formula (I) wherein a fluorinated nitrated benzene compound of formula (II) is subjected to a catalytic hydrogenation in a liquid medium containing a catalyst, under hydrogen pressure, carrying out a catalytic reduction reaction and, optionally, a hydrogenolysis reaction, wherein the compound of formula (II) is introduced gradually into the said medium so that the content of compound of formula (II) in the liquid remains less than or equal to 1000 ppm by mass, in order selectively to form the compound of formula (I).
Claims24
A process for the preparation of a compound of formula (I):
- ##STR20## wherein n has a value from 1 to 5;
- Z is a radical which is stable under catalytic hydrogenation conditions;
- and
- p is less than 5-n;
- comprising the step of subjecting a compound of formula (II):
- ##STR21## wherein n, Z and p have the above meanings;
- X is a hydrogenolysable radical;
- and
- q has a value from 0 to 5-(n+p);
- to a catalytic hydrogenation in a liquid medium containing a catalyst, under hydrogen pressure in order to carry out a catalytic reduction reaction and, optionally, a hydrogenolysis reaction, wherein the compound of formula (II) is introduced gradually into the said liquid medium so that the content of compound of formula (II) in the liquid medium remains less than or equal to 1000 ppm by mass, in order selectively to form the compound of formula (I).
Dependencies are inferred from the claim text.