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US 5,856,519 AGranted
Chiral auxilary for stereoselective alkylations
AssigneeMerck & Co., Inc.
InventorsPaul N. Devine, Richard M. Heid, Jr., David M. Tschaen
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Abstract
This invention relates to a method for the stereoselective synthesis of a 2-aryloxycarboxylic acid using a chiral auxiliary to enhance the stereoselectivity of the alkylation of the .alpha.-halo acid with an aryloxy group.
Claims1
A compound of formula:
- ##STR45## wherein R.sup.a is (C.sub.4 -C.sub.6)-alkyl or cyclohexyl.
Dependencies are inferred from the claim text.