Oligonucleotides to inhibit the expression of isoprenyl protein transferases
AssigneeSociete de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
InventorsSoudhir Colote, Eduardo Pirotzky
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Abstract
The invention relates to oligonucleotides and their derivatives to inhibit the expression of isoprenyl protein transferases, therapeutic compositions containing such compounds and the use of such compositions of oligonucleotides for the treatment or therapy of diseases of the human or animal body induced by an abnormal and/or uncontrolled cellular proliferation.
Claims6
An antisense oligonucleotide which selectively hybridizes with a gene or a transcription product for a subunit of an isoprenyl protein transferase and which inhibits cellular proliferation, said oligonucleotide selected from the group consisting of SEQ ID NOS:
- 1 to 3, 5 to 7, 23 and 33 to 36.
Dependencies are inferred from the claim text.