Nucleic acids encoding a human IL-8 receptor
AssigneeGenentech, Inc.
InventorsJames Lee, William E. Holmes, William I. Wood
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Abstract
The cDNA encoding a member of or a class of novel PF4A receptors has been identified in human tissue. Provided herein is nucleic acid sequence of a PF4A receptor (the IL-8 receptor) useful as a diagnostic and in the recombinant preparation of PF4A receptors. The PF4A receptor is used in the preparation and purification of antibodies capable of binding to the receptor, and in diagnostic assays.
Claims7
An isolated nucleic acid molecule encoding a PF4A receptor polypeptide comprising the N-terminal extracellular region contained in the human IL-8 receptor polypeptide amino acid sequence of SEQ ID NO:1.
A DNA molecule comprising greater than about 45 contiguous nucleotides contained in or complementary to the DNA sequence of SEQ ID NO:2.
Dependencies are inferred from the claim text.