Hybridomas producing antibodies specific for lyme disease antigens OspA and OspB
AssigneeMax-Planck-Gesellschaft zur Forderung der Wissenschaften
InventorsMarkus M. Simon, Ulrich E. Schaible, Klaus Eichmann, Michael Kramer, Wallich Reinhard
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Abstract
The present invention provides a vaccine against Lyme disease, wherein it contains one or more monoclonal antibodies which are specific for the 31 kD antigen (OspA) or the 34 kD antigen (OspB) of Borrelia burgdorferi. The present invention also provides a process for obtaining this vaccine, as well as new monoclonal antibodies, hybridomas and antigens.
Claims8
Monoclonal antibody LA-2 against OspA secreted by the hybridoma cell line ECACC 89091302.
Monoclonal antibody LA 26.1 against OspA secreted by the hybridoma cell line ECACC 90050406.
Monoclonal antibody LA 25.1 against OspB secreted by the hybridoma cell line ECACC 90050405.
Monoclonal antibody LA 27.1 against OspB secreted by the hybridoma cell line ECACC 90050407.
Dependencies are inferred from the claim text.