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US 5,856,351 AGranted
Artemisinin dimer compounds having anticancer activity
OwnerQun Y. Zheng, Lynn G. Darbieinventors
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Abstract
Novel artemisinin dimers of structure ##STR1## which possess anticancer activity.
Claims22
A method for treating cancer, which comprises administering to a patient suffering from said cancer an artemisinin dimer of the formula:
- ##STR10## or an isomer thereof where R is a linker.
A method for treating cancer, which comprises administering to a patient suffering from said cancer an artemisinin dimer of formula:
- ##STR11## or an isomer thereof wherein X is a bivalent ester, carbonate, or carbamate species carbonyl, and R is alkylene, alkenylene, arylene, a bivalent halide species, or polyethylene glycol.
A method for treating cancer, which comprises administering to a patient suffering from said cancer an artemisinin dimer of the formula:
- ##STR15## or an isomer thereof, wherein n is 1-20.
A method for treating cancer, which comprises administering to a patient suffering from said cancer an artemisinin dimer of the formula:
- ##STR16## or an isomer thereof.
Dependencies are inferred from the claim text.