Benzo ›B! indeno ›2,1-D! thiophene compounds, intermediates, processes, compositions and methods

A compound of formula I:

• ##STR29## wherein:
• R.sup.1 is --H, --OH, --X, where --X is a halogen, --O(C.sub.1 -C.sub.4 alkyl), --OCO(C.sub.1 -C.sub.6 alkyl), --OCO(O)(C.sub.1 -C.sub.6 alkyl), --OCOAr, --OCO(O)Ar where Ar is phenyl or substituted phenyl, or --OSO.sub.2 (C.sub.4 -C.sub.6 alkyl);
• R.sup.2, R.sup.3, and R.sup.4 are independently --H, --OH, --X, where --X is a halogen, --O(C.sub.1 -C.sub.4 alkyl), --OCO(C.sub.1 -C.sub.6 alkyl), --OCO(O) (C.sub.1 -C.sub.6 alkyl), --OCOAr, --OCO(O)Ar where Ar is phenyl or substituted phenyl, or --OSO.sub.2 (C.sub.4 -C.sub.6 alkyl);
• n is 2 or 3;
• R.sup.5 is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidinyl, 4-morpholino, dimethylamino, diethylamino, or 1-hexamethyleneimino;
• and
• R.sup.6 is --H, --OH, --X, where --X is a halogen, --CN, --NH.sub.2, --NHR.sup.8, --NR.sup.8 R.sup.9, where R.sup.8 and R.sup.9 are both independently C.sub.1 -C.sub.6 alkyl, or C.sub.1 -C.sub.6 alkyl;
• or a pharmaceutically acceptable salt or solvate thereof.