Back to results
US 5,856,320 AGranted
Cephem compounds, their preparation and their use as antimicrobial agents
AssigneeKatayama Seiyakusyo Co., Ltd.
InventorsSadao Hayashi, Yasuyuki Kurita
Life of this patent
Estimating the term…
Abstract
Novel cephalosporin derivatives of formula (II): ##STR1## wherein R.sup.2 is hydrogen, methyl, or fluoromethyl; R.sup.3 is hydrogen, methyl or carboxyl; R.sup.4 is hydrogen or methyl; A is methylene or propenylene; Q is nitrogen or CH, and pharmaceutically acceptable salts, solvates, hydrates and esters thereof, a process for their preparation and an antimicrobial composition containing them.
Claims6
A compound of formula (I):
- ##STR36## wherein R.sup.1 is hydrogen or an amino protecting group;
- R.sup.2 is hydrogen, a lower alkyl or fluoromethyl;
- R.sup.3 is hydrogen, a lower alkyl, carboxyl or a protected carboxyl group;
- R.sup.4 is hydrogen or a lower alkyl;
- R.sup.5 is hydrogen, an anion or a carboxyl-protecting group;
- A is methylene or propenylene;
- X is an organic or inorganic anion, provided that X is excluded when R.sup.5 is an anion;
- Q is nitrogen or CH, and the wavy line represents a bond of anti-form or syn-form, or a pharmaceutically acceptable salt thereof.
5 more elements
An antimicrobial composition which comprises as an active ingredient at least one of the compounds of formula (II):
- ##STR37## wherein R.sup.2 is hydrogen, methyl or fluoromethyl;
- R.sup.3 is hydrogen, methyl or carboxyl;
- R.sup.4 is hydrogen or methyl;
- A is methylene or propenylene;
- Q is nitrogen or CH, and the wavy line represents a bond of syn-form, or a pharmaceutically acceptable salt thereof, with an inert carrier or diluent.
2 more elements
Dependencies are inferred from the claim text.