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US 5,856,129 AGranted
DNA encoding a human purinoceptor
AssigneeIncyte Pharmaceuticals, Inc.
InventorsJennifer L. Hillman, Roger Coleman
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AssigneeIncyte Pharmaceuticals, Inc.
InventorsJennifer L. Hillman, Roger Coleman
Estimating the term…
The present invention provides a novel human P.sub.2X purinoreceptor (HPURR) and polynucleotides which identify and encode HPURR. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPURR and a method for producing HPURR. The invention also provides for use of HPURR, and agonists, antibodies or antagonists specifically binding HPURR, in the prevention and treatment of diseases associated with expression of HPURR. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HPURR for the treatment of diseases associated with the expression of HPURR. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HPURR.
An isolated and purified polynucleotide molecule encoding the amino acid sequence of SEQ ID NO:1.
An isolated and purified polynucleotide molecule comprising SEQ ID NO:2.
An isolated and purified polynucleotide molecule comprising a sequence which is complementary to SEQ ID NO:2.
Dependencies are inferred from the claim text.