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US 5,855,901 AGranted
Immunostimulating activity of Streptococcus pneumoniae serotype 8 oligosaccharides
AssigneeAlberta Research Council
InventorAndrew J. Malcolm
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Abstract
The invention provides compositions comprising an oligosaccharide of S. pneumoniae serotype 8 useful for stimulating an immune response to an antigen, methods of providing protective immunization against a bacterial pathogen using these compositions, methods of augmenting an immunogenic response to an antigen by administering these S. pneumoniae serotype 8 oligosaccharide compositions along with the antigen, and methods of making the immunostimulatory compositions described above.
Claims3
A composition useful for stimulating an inmune response to an antigen, said immunostimulatory composition consisting essentially of:
- a) an antigen, which antigen is not an oligosaccharide of S. pneumoniae serotype 8 and which antigen is not attached to an oligosaccharide of S. pneumoniae serotype 8;
- b) an oligosaccharide of S. pneumoniae serotype 8 which contains an immunogenic epitope;
- and
- c) a suitable pharmaceutical excipient, wherein said oligosaccharide of S. pneumoniae serotype 8 stimulates or enhances an immune response to the antigen when said composition is administered to an animal.
1 more element
Dependencies are inferred from the claim text.