Supramolecular-structured biodegradable polymeric assembly for drug delivery
OwnerYui Nobuhikoinventor
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Abstract
This invention provides as a novel drug carrier into a living body a highly water-soluble polymer that can carry and release a drug at a desired rate and a supramolecular-structured biodegradable polymeric assembly that can release the drug it carries as a function of the specific behavior of biodegradation of a diseased body. A supramolecular-structured biodegradable polymeric assembly according to the invention comprises lots of drug-binding cyclic compounds obtained by combining the drug with .alpha.-, .beta.- and .gamma.-cyclodextrins and a linear polymeric chain compound threading through the structural cavity of the cyclic compounds, said linear polymeric chain with biodegradable sites at the both terminals thereof.
Claims8
A supramolecular-structured biodegradable polymeric assembly, comprising:
- a drug-binding cyclic compound obtained by combining a drug with at least one cyclodextrin selected from the group consisting of .alpha.-cyclodextrin, .beta.-cyclodextrin, and .gamma.-cyclodextrin via one of ester bonding or urethane bonding, and
- a polymeric material having a linear polymeric chain which passes through the structural cavity of the cyclodextrin, and which has biodegradable sites at both terminals of the linear polymeric chain.
Dependencies are inferred from the claim text.