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US 5,855,825 AGranted
Process for producing ocular lens and ocular lens produced by the process
AssigneeMenicon Co., Ltd.
InventorEri Ito
Life of this patent
Estimating the term…
Abstract
A process for producing an ocular lens characterized by mixing a polymerizable component for an ocular lens with an organic solvent (I) capable of dissolving the polymerizable component, injecting the obtained mixture into a mold having the desired shape for an ocular lens and then, preparing a polymer by the polymerization reaction, immersing the polymer taken off from the mold in an aqueous organic solvent (II) having compatibility with the organic solvent (I), and then, hydrating the polymer, and an ocular lens produced by the process, which is, in particular, remarkably excellent in transparency.
Claims20
A process for producing a contact lens comprising:
- mixing a polymerizable component for an ocular lens containing
- 3 to 85% by weight of a silicon-containing alkyl acrylate, and a polysiloxane. macromonomer in which a polymerizable group bonds to a siloxane main chain through one or two urethane bonds, and which is represented by the formula (X):
- ##STR10## wherein each of Y.sup.41 and Y.sup.42 is independently acryloyl group, methacryloyl group, vinyl group or allyl group, each of R.sup.51 and R.sup.54 is independently a linear or branched alkylene group having 2 to 6 carbon atoms, each of X.sup.41 and X.sup.42 is independently a covalent bond, oxygen atom or an alkylene glycol, each of R.sup.52 and R.sup.53 is independently a linear or branched alkylene group having 1 to 6 carbon atoms, each of R.sup.43, R.sup.44, R.sup.45, R.sup.46, R.sup.47 and R.sup.41 is independently an alkyl group having 1 to 3 carbon atoms or phenyl group, each of E.sup.41 and E.sup.42 is independently --NHCO-- (in this case, X.sup.41 and X.sup.42 are covalent bonds, an urethane bond is formed between E.sup.41 and X.sup.45, and an urethane bond is formed between E.sup.42 and X.sup.46) or a divalent group derived from a diisocyanate selected from a saturated aliphatic diisocyanate, an alicyclic diisocyanate and an aromatic diisocyanate (in this case, each of X.sup.41 and X.sup.42 is independently oxygen atom or an alkylene glycol group, E.sup.41 forms an urethane bond between X.sup.41 and X.sup.45, and E.sup.42 forms an urethane bond between X.sup.42 and X.sup.46), each of X.sup.45 and X.sup.46 is independently oxygen atom, an alkylene glycol group or a group represented by the formula (XI):
- ##STR11## in which R.sup.61 is a trivalent hydrocarbon group having 1 to 6 carbon atoms, Y.sup.41 is acryloyloxy group, methacryloyloxy group, vinyl group or allyl group, R.sup.56 is a linear or branched alkylene group having 2 to 6 carbon atoms, X.sup.43 is a covalent bond, oxygen atom or an alkylene glycol group, E.sup.43 is --NHCO-- (in this case, X.sup.43 is a covalent bond) or a divalent group derived from a diisocyanate selected from a saturated aliphatic diisocyanate, an alicyclic diisocyanate and an aromatic diisocyanate (in this case, X.sup.43 is oxygen atom or an alkylene glycol group) and in which each of X.sup.45 and X.sup.46 forms an urethane bond between neighboring oxygen atom bonding to R.sup.61 and X.sup.43, m1 is an integer of 1 to 1500, and m2 is an integer of 0 to 1499 (also, (m1+m2).ltoreq.1500),
- 10to 95% by weight of a hydroxyalkyl (meth)acrylate (B), and
- 0.01 to 10% by weight of a crosslinkable compound (C) having at least two polymerizable groups;
- with at least one member of butanol and pentanol which can dissolve the polymerizable component,
- injecting the obtained mixture into a mold having the desired shape for a contact lens and then,
- preparing a polymer by the polymerization reaction,
- immersing the polymer taken off from said mold in at least one member of ethanol and propanol which have compatibility with at least one member of butanol and pentanol, and then,
- hydrating said polymer;
- and wherein the weight ratio of the polymerizable component for an ocular lens to at least one member of butanol and pentanol (polymerizable component/at least one member of butanol and pentanol) is 50/50 to 66/34.
9 more elements
An ocular lens material comprising a polymer prepared by polymerizing a polymerizable component for an ocular lens containing
- 3 to 85% by weight of a silicon-containing alkyl acrylate, and a polysiloxane macromonomer in which a polymerizable group bonds to a siloxane main chain through one or two urethane bonds, and which is represented by the formula (X):
- ##STR16## wherein each of Y.sup.41 and Y.sup.42 is independently acryloyl group, methacryloyl group, vinyl group or allyl group, each of R.sup.51 and R.sup.54 is independently a linear or branched alkylene group having 2 to 6 carbon atoms, each of X.sup.41 and X.sup.42 is independently a covalent bond, oxygen atom or an alkylene glycol, each of R.sup.52 and R.sup.53 is independently a linear or branched alkylene group having 1 to 6 carbon atoms, each of R.sup.43, R.sup.44, R.sup.45, R.sup.46, R.sup.47 and R.sup.48 is independently an alkyl group having 1 to 3 carbon atoms or phenyl group, each of E.sup.41 and E.sup.42 is independently --NHCO-- (in this case, X.sup.41 and X.sup.42 are covalent bonds, an urethane bond is formed between E.sup.41 and X.sup.45, and an urethane bond is formed between E.sup.42 and X.sup.46) or a divalent group derived from a diisocyanate selected from a saturated aliphatic diisocyanate, an alicyclic diisocyanate and an aromatic diisocyanate (in this case, each of X.sup.41 and X.sup.42 is independently oxygen atom or an alkylene glycol group, E.sup.41 forms an urethane bond between X.sup.41 and X.sup.45, and E.sup.42 forms an urethane bond between X.sup.42 and X.sup.46), each of X.sup.45 and X.sup.46 is independently oxygen atom, an alkylene glycol group or a group represented by the formula (XI):
- ##STR17## in which R.sup.61 is a trivalent hydrocarbon group having 1 to 6 carbon atoms, Y.sup.43 is acryloyloxy group, methacryloyloxy group, vinyl group or allyl group, R.sup.56 is a linear or branched alkylene group having 2 to 6 carbon atoms, X.sup.43 is a covalent bond, oxygen atom or an alkylene glycol group, E.sup.43 is --NHCO-- (in this case, X.sup.43 is a covalent bond) or a divalent group derived from a diisocyanate selected from a saturated aliphatic diisocyanate, an alicyclic diisocyanate and an aromatic diisocyanate (in this case, X.sup.43 is oxygen atom or an alkylene glycol group) and in which each of X.sup.45 and X.sup.46 forms an urethane bond between neighboring oxygen atom bonding to R.sup.61 and X.sup.43, m1 is an integer of 1 to 1500, and m2 is an integer of 0 to 1499 (also, (m1+m2).ltoreq.1500),
- 10to 95% by weight of a hydroxyalkyl (meth)acrylate (B), and
- 0.01 to 10% by weight of a crosslinkable compound (C) having at least two polymerizable groups.
2 more elements
Dependencies are inferred from the claim text.