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US 5,854,486 AGranted
Method and apparatus for MALDI mass spectrometry
AssigneeR. T. Hodgson
InventorRussell W. Dreyfus
Life of this patent
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Abstract
A thin uniform film of matrix material is deposited from the gas phase on to a substrate for use in Matrix Assisted Laser Desorption and Ionization (MALDI) spectroscopy. The thin uniform film of material may be overcoated with another film of material which has a higher vapor pressure than the matrix material to prevent the matrix material from evaporating during storage and during substantial time in the vacuum environment of the mass spectrometer.
Claims7
An apparatus for Matrix Assisted Laser Desorption and Ionization (MALDI) Mass Spectrometry comprising;
- a substrate;
- and
- a first layer deposited on the substrate, the first layer comprising molecules of matrix material, the first layer being substantially free of pinholes, the first layer having an average thickness between 1 nanometer and 10 micrometers.
Dependencies are inferred from the claim text.