Methods for the diagnosis of glaucoma
AssigneeThe Regents of the University of California
InventorsThai D. Nguyen, Jon R. Polansky, Weidong Huang
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Abstract
A glucocorticoid-induced protein, TIGR, that is produced by cells of the trabeclar meshwork can be used to diagnose glaucoma. The TIGR protein, anti-TIGR antibodies, and TIGR encoding sequences also provide a diagnostic for glaucoma and its related diseases.
Claims10
A substantially purified nucleic acid molecule that encodes the secretory protein of clone II.2.
A substantially purified nucleic acid molecule which comprises an oligonucleotide fragment between about 15 to about 250 nucleotides of a nucleic acid molecule that encodes the secretory protein of clone II.2.
A substantially purified nucleic acid molecule that specifically hybridizes with a nucleic acid molecule that encodes the secretory protein of clone II.2, wherein said substantially purified nucleic acid molecule is complementary to said nucleic acid molecule encoding the secretory protein of clone II.2.
A substantially purified clone II.2.
Dependencies are inferred from the claim text.