Antibodies specific for human cripto-related polypeptide CR-3
AssigneeThe United States of America as represented by the Department of Health and Human Services
InventorsDavid S. Salomon, Maria G. Persica
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Abstract
The present invention relates, in general, to a human CRIPTO-related gene. In particular, the present invention relates to a DNA segment encoding a human CRIPTO-related gene; polypeptides encoded by said DNA segment; recombinant DNA molecules containing the DNA segment; cells containing the recombinant DNA molecule; a method of producing a human CRIPTO-related polypeptide; a DNA segment encoding a genomic clone of the human CRIPTO gene (CR-1); antibodies specific to CR-3; and a method of measuring the amount of CR-3 in a sample.
Claims2
An antibody having binding affinity to a human CRIPTO-related polypeptide-3 (CR-3) and not to CR-1, wherein said CR-3 has the amino acid sequence set forth in SEQ ID NO:5.
Dependencies are inferred from the claim text.