Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
AssigneeYukong Limited
InventorsYong Moon Choi, Min Woo Kim, Jeonghan Park
Life of this patent
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Abstract
The optically pure forms of monoocarbamates of halogenated 2-phenyl-1,2-ethanediol and dicarbamates of 2-phenly-1,2-ethaniediol have been found to be effective in the treatment of disorders of the central nervous system, especially as anti-convulsive or anti-epileptic agents.
Claims6
Pure enantiomeric forms, as well as enantiomeric mixtures wherein one enantiomer of 2-phenyl-1,2-ethanediol carbamate compounds represented by structural formula (I) predominates, wherein the phenyl ring is substituted with a chlorine atom at the ortho position and R.sub.1 and R.sub.2 are both hydrogen ##STR10##
Pure enantiomeric forms, as well as enantiomeric mixtures wherein one enantiomer of 2-phenyl-1,2-ethanediol carbamate compounds represented by structural formula (II) predominates, wherein the phenyl ring is substituted with a chlorine atom at the ortho position and R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are all hydrogen ##STR11##
Pure enantiomeric forms, as well as enantiomeric mixtures wherein one enantiomer of 2-phenyl-1,2-ethanediol carbamate compounds represented by structural formula (I) predominates, wherein the phenyl ring is substituted with a chlorine atom at the ortho position, R.sub.1 and R.sub.2 are both hydrogen and said one enantiomer is present to the extent of 98% or greater ##STR12##
Pure enantiomeric forms, as well as enantiomeric mixtures wherein one enantiomer of 2-phenyl-1,2-ethanediol carbamate compounds represented by structural formula (II) predominates, wherein the phenyl ring is substituted with a chlorine atom at the ortho position, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are all hydrogen, and said one enantiomer is present to the extent of 98% of greater ##STR13##
Dependencies are inferred from the claim text.