Oral compositions containing ondansetron
AssigneeGlaxo Wellcome Inc.
InventorRenu Gambhir
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Abstract
The invention relates to a liquid composition for oral administration comprising ondansetron or a pharmaceutically acceptable derivative thereof, a sweetener and one or more pharmaceutically acceptable excipients. The sweetener comprises one or more polyhydric alcohols and the pH of the combination lies in the range 2.0 to 5.0. Methods for the manufacture of such compositions and for their use in the treatment of conditions mediated through the action of 5-hydroxytryptamine (5 HT) at 5 HT.sub.3 receptors are also included.
Claims12
A liquid composition for oral administration comprising ondansetron or a pharmaceutically acceptable derivative thereof, a sweetener and one or more pharmaceutically acceptable excipients, characterised in that the sweetener comprises sorbitol and the pH of the composition lies in the range 2.0 to 5.0.
Dependencies are inferred from the claim text.