Synergistic antimicrobial composition pyrithione and alcohol
AssigneeOlin Corporation
InventorJohn D. Nelson, Jr.
Life of this patent
Estimating the term…
Abstract
Disclosed herein is an antimicrobial composition characterized by synergistic antibacterial efficacy against Gram-negative bacteria and comprising an antimicrobially effective amount of a pyrithione salt or pyrithione acid, and an alcohol, preferably an aromatic alcohol. Also disclosed is a method of imparting antimicrobial activity to a composition comprising water or an organic solvent which comprises adding thereto an antimicrobially effective amount of the above-described antimicrobial composition.
Claims12
A method of imparting antimicrobial activity to a composition comprising water or an aqueous organic solvent which comprises adding thereto an antimicrobial composition consisting essentially of at least 2 ppm of pyrithione acid or a pyrithione salt, or a combination thereof, and an aromatic alcohol selected from the group consisting of phenylethyl alcohol, benzyl alcohol, 3-phenyl-1-propyl alcohol, 2-phenoxyethanol, and combinations thereof, said aromatic alcohol being present in a weight ratio between 1,250:1 and 5:1 based upon the weight of said pyrithione acid or said pyrithione salt, or combination thereof, in said antimicrobial composition.
A method of coating a substrate to provide an antimicrobially effective coating on the substrate which comprises contacting the substrate with a coating composition comprising an antimicrobial composition consisting essentially of at least 2 ppm of pyrithione acid or a pyrithione salt, or a combination thereof, and an aromatic alcohol selected from the group consisting of phenylethyl alcohol, benzyl alcohol, 3-phenyl-1-propyl alcohol. 2-phenoxyethanol, and combinations thereof, said aromatic alcohol being present in a weight ratio between 1.250:1 and 5:1 based upon the weight of said pyrithione acid or said pyrithione salt, or combination thereof, in said antimicrobial composition.
A coated substrate comprising a substrate together with a coating on said substrate, said coating being produced by:
- (a) contacting the substrate with a coating composition comprising an antimicrobial composition consisting essentially of at least 2 ppm of pyrithione acid or a pyrithione salt, or a combination thereof, and an aromatic alcohol selected from the group consisting of phenylethyl alcohol, benzyl alcohol, 3-phenyl-1-propyl alcohol. 2-phenoxyethanol, and combinations thereof, said aromatic alcohol being present in a weight ratio between 1.250:1 and 5:1 based upon the weight of said pyrithione acid or said pyrithione salt, or combination thereof, in said antimicrobial composition, to provide a coating on said substrate, and
- (b) drying said coating composition on said substrate to produce said coated substrate.
A paint comprising:
- (a) a base medium comprising water or a resin selected from the group consisting of vinyl, alkyd, epoxy, acrylic, polyurethane and polyester resins, and combinations thereof, and
- (b) a biocide comprising an antimicrobial composition consisting essentially of at least 2 ppm of pyrithione acid or a pyrithione salt, or a combination thereof, and an aromatic alcohol selected from the group consisting of phenylethyl alcohol, benzyl alcohol, 3-phenyl-1-propyl alcohol, 2-phenoxyethanol, and combinations thereof, said aromatic alcohol being present in a weight ratio between 1.250:1 and 5:1 based upon the weight of said pyrithione acid or said pyrithione salt, or combination thereof, in said antimicrobial composition, said biocide being present in an amount at least sufficient to provide inhibition of microbial growth during in-can storage of the paint.
A soap, shampoo or skin care medicament comprising a suitable carrier and an antimicrobial composition consisting essentially of at least 2 ppm of pyrithione acid or a pyrithione salt, or a combination thereof, and an aromatic alcohol selected from the group consisting of phenylethyl alcohol, benzyl alcohol, 3-phenyl-1-propyl alcohol, 2-phenoxyethanol, and combinations thereof, said aromatic alcohol being present in a weight ratio between 1.250:1 and 5:1 based upon the weight of said pyrithione acid or said pyrithione salt, or combination thereof, in said antimicrobial composition.
A metalworking fluid containing water or an organic base fluid and an antimicrobial composition consisting essentially of at least 2 ppm of pyrithione acid or a pyrithione salt, or a combination thereof, and an aromatic alcohol selected from the group consisting of phenylethyl alcohol, benzyl alcohol, 3-phenyl-1-propyl alcohol. 2-phenoxyethanol, and combinations thereof, said aromatic alcohol being present in a weight ratio between 1,250:1 and 5:1 based upon the weight of said pyrithione acid or said pyrithione salt, or combination thereof, in said antimicrobial composition.
A composition comprising a plastic or a woven or non-woven fiber which comprises, in combination, a plastic or a fiber and an antimicrobial composition consisting essentially of at least 2 ppm of pyrithione acid or a pyrithione salt, or a combination thereof, and an aromatic alcohol selected from the group consisting of phenylethyl alcohol, benzyl alcohol. 3-phenyl-1-propyl alcohol, 2-phenoxyethanol, and combinations thereof, said aromatic alcohol being present in a weight ratio between 1.250:1 and 5:1 based upon the weight of said pyrithione acid or said pyrithione salt, or combination thereof, in said antimicrobial composition.
Dependencies are inferred from the claim text.