Methylene blue for the treatment or prophylaxis of encephalopathy caused by ifosfamide
AssigneeNewcastle University Ventures Limited
InventorsAdrian Kupfer, Thomas Cerny
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Abstract
The encephalopathy caused by ifosfamide and similarly acting compounds can be prevented or treated by the administration of methylene blue or another compound which is able to oxidize a reduced flavin moiety. Pyritinol is able to reduce other aspects of ifosfamide toxicity.
Claims7
A method of treating or preventing toxicity caused by ifosfamide, the method comprising administering to a subject in need thereof an effective amount of a compound which is able to oxidize a reduced flavin moiety, wherein the compound is methylene blue.
A method of treating or preventing ifosfamide encephalopathy, the method comprising administering to a subject in need thereof an effective amount of methylene blue.
Dependencies are inferred from the claim text.