Murine and humanizer 23F2G antibodies and cell lines expressing said antibodies
AssigneesICOS Corporation, The Board of Regents of the University of Washington
InventorLynn M. Rose
Life of this patent
Estimating the term…
Abstract
Disclosed are methods for the alleviation of symptoms associated with inflammatory disease states, and more particularly to the inhibition of inflammatory processes associated with the multiple sclerosis disease, by administering a pharmaceutically effective amount of antibody substance immunologically reactive with the common .beta. chain (CD18) of human leukocyte integrins and/or competes with mAb 60.3 for binding to human LFA-1.
Claims6
Hybridoma cell line 23F2G, A.T.C.C. HB 11801.
Monoclonal antibody 23F2G produced by hybridoma cell line 23F2G, A.T.C.C 11081.
CHO cell line 6E6, A.T.C.C. CRL11398.
Monoclonal antibody 6E6 produced by CHO cell line 6E6, A.T.C.C. CRL11398.
CHO cell line B13-24, A.T.C.C. CRL11397.
Monoclonal antibody B13-24 produced by CHO cell line B13-24, A.T.C.C. CRL11397.
Dependencies are inferred from the claim text.