Parasitic helminth asparaginase proteins, nucleic acid molecules, and uses thereof
AssigneesHeska Corporation, Colorado State University Research Foundation
InventorsRamaswamy Chandrashekar, Naotoshi Tsuji
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Abstract
The present invention relates to: parasitic helminth asparaginase proteins; parasitic helminth asparaginase nucleic acid molecules, including those that encode such asparaginase proteins; antibodies raised against such asparaginase proteins; and compounds that inhibit parasitic helminth asparaginase activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to protect animals from diseases caused by parasitic helminths.
Claims9
An isolated nucleic acid molecule comprising a nucleic acid sequence encoding a Dirofilaria immitis asparaginase protein, or its complementary sequence.
A method to produce a Dirofilaria immitis asparaginase protein comprising culturing in an effective medium a recombinant cell as
Dependencies are inferred from the claim text.