Localization of a therapeutic agent in a cell in vitro
AssigneeUniversity Research Corporation
InventorsBruce Alan Sullenger, Thomas Robert Cech
Life of this patent
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Abstract
Method for enhancing the effect of a viral therapeutic agent in a cell in vitro on the viral target by tethering a localization signal to the therapeutic agent so that the agent localizes with the viral target in a cellular or viral compartment of the cell.
Claims13
A method for enhancing the effect of a viral therapeutic agent in a cell in vitro on the viral target of said agent, comprising the step of:
- tethering a localization signal to said therapeutic agent wherein said localization signal causes said therapeutic agent to be localized with said viral target in a cellular or viral compartment of said cell.
A viral therapeutic agent comprising at least one localization signal able to localize said agent in the same cellular or viral compartment with a viral target of said therapeutic agent in a cell in vitro.
A therapeutic agent comprising a localization signal, wherein said localization signal is capable of localizing said therapeutic agent in the same cellular compartment as the target molecule of said therapeutic agent in a cell in vitro.
Dependencies are inferred from the claim text.