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US 5,853,761 AGranted
Stabilizing agent for oleaginous, physiologically active substances
AssigneeFujisawa Pharmaceutical Co., Ltd.
InventorsKiyoshi Kumabe, Hiroyuki Yanaka, Takayuki Kondo, Jun Shirai
Life of this patent
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Abstract
The invention relates to a solid preparation containing an oleaginous, physiologically active substance which comprises the oleaginous, physiologically active substance, calcium gluconate, a reticular matrix-forming agent, and a sticking agent. It is a stable preparation which does not give off an odor even when added to a beverage or the like.
Claims14
A composition consisting essentially of:
- a substance having an objectionable odor selected from the group consisting of docosahexaenoic acid (DHA), eicosahexaenoic acid (EPA), fat-soluble vitamins and carotenes;
- an effective amount of calcium gluconate to mask the odor of said substance, and
- a reticular matrix-forming agent selected from the group consisting of milk calcium, milk casein milk casein hydrolyzates and pectin.
A process for producing a composition having a masked odor, comprising:
- mixing a substance having an objectionable odor selected from the group consisting of docosahexaenoic acid (DHA), eicosahexaenoic acid (EPA), fat-soluble vitamines and carotens, with an effective amount of calcium gluconate to mask the odor of said substance and a reticular matrix-forming agent selected from the group consisting of milk calcium, milk casein, milk casein hydrolyzates and pectin under stirring, then drying the mixture.
Dependencies are inferred from the claim text.