Device for the controlled release of active substances
AssigneeLTS Lohmann Therapie-Systeme AG
InventorKarsten Cremer
Life of this patent
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Abstract
A device for the controlled release of active substances in liquid media from an active substance-containing matrix exhibiting active substance releasing-surfaces has, the active substance releasing surfaces of the matrix covered, at least partially, by an erodible mass of solids; the thickness of the erodible mass across its extent on the active substance releasing-areas is determined by gradients.
Claims14
A device for the controlled release of at least one active substance into a liquid medium comprising
- a controlled release active substance-containing matrix, said matrix having an active substance releasing surface, and
- at least one covering layer containing a solid material which is erodible in said liquid medium, said covering layer covering at least partially said active substance releasing surface of said matrix,
- wherein said covering layer has a thickness profile with at least one thickness gradient different from zero and wherein the erosion of said covering layer having said thickness profile effects a controlled and continuous uncovering of said partially covered active substance releasing surface.
A method for the controlled administration of an active substance comprising a drug to a patient, which method comprises
- administering to said patient a device for the controlled release of said active substance drug into a liquid medium and said device comprising
- a controlled release active substance-containing matrix, said matrix having an active substance releasing surface, and
- at least one covering layer containing a solid material which is erodible in said liquid medium, said covering layer covering at least partially said active substance releasing surface of said matrix,
- wherein said covering layer has a thickness profile with at least one thickness gradient different from zero and wherein the erosion of said covering layer having said thickness profile effects a controlled and continuous uncovering of said partially covered active substance releasing surface.
A method for the controlled delivery of an active substance to a plant which comprises
- incorporating into a liquid medium to be applied to said plant or to the locus of said plant, wherein said active substance is an agent for plant protection,
- a device for the controlled release of said active substance into said liquid medium comprising
- a controlled release active substance-containing matrix, said matrix having an active substance releasing surface, and
- at least one covering layer containing a solid material which is erodible in said liquid medium, said covering layer covering at least partially said active substance releasing surface of said matrix,
- wherein said covering layer has a thickness profile with at least one thickness gradient different from zero and wherein the erosion of said covering layer having said thickness profile effects a controlled and continuous uncovering of said partially covered active substance releasing surface;
- and
- applying said liquid medium to said plant or to the locus of said plant,
- is a fertilizer, and subsequently applying said liquid to said plant or to the locus of said plant.
Dependencies are inferred from the claim text.